TABLE 1.

Identification of L2 domains interacting with L1a

DomainInteraction with wt L1Interaction with L1ΔNLS
VLP incorporationND10 attractionVLP incorporationND10 attraction
wt L2 (1/467)YesYesYesYes
L2-1/456YesYesNoNo
L2-1/420YesYesNTNo
L2-1/360YesNo*NTNo*
L2-1/330YesNo*NoNo*
L2-1/300YesNo*NoNo*
L2-12/467NTYesNTNo
L2-91/467NTYesNTNo
L2-150/467YesYesNoNo
L2-360/467NTYesNTNT
  • a *, mutants that do not accumulate in ND10; NT, not tested.