TABLE 3

Comparison of viral RNA and viral DNA levels in controls and treated macaques

ParameterbValue for groupP valuea
Controls (n = 12)830A (n = 18)
MedianMeanSDMedianMeanSD
SIV gag RNA copies per million cells
    PVL AUC5.3 × 1077.7 × 1077.5 × 1072.1 × 1073.7 × 1074.2 × 1070.1632
    Peak PVL5.3 × 1067.4 × 1066.3 × 1062.1 × 1063.3 × 1063.6 × 1060.1007
SIV gag DNA copies per million cells
    CAVL AUC2.7 × 1052.9 × 1052.1 × 1059.2 × 1041.3 × 1051.3 × 1050.0437
    Tissue vDNA1.4 × 1041.5 × 1041.0 × 1049.1 × 1028.1 × 1026.7 × 1020.0487
  • a Wilcoxon rank sum P value.

  • b AUC, area under the curve; vDNA, viral DNA. Tissue vDNA is the mean value for all tissues analyzed in each macaque in each group.