Table 7.

Genes modulated by UV-HCMV but not HCMV

GeneNuc IDaHCMV fold changebUV-HCMV fold changeb
37-kDa leucine-rich repeat (LRR) protein U32907 1.2, −1.5∼−8.4, ∼−8.5
ATPase, class V, type 10D AB025254 1.5, 1.59.1, 8.1
ATP-binding cassette, subfamily A (ABC1), member 6 AI651024 1.1, 1.1∼−6.5, ∼−7.1
ATP-binding cassette, subfamily B (MDR/TAP), member 2 X57522 1.7, 1.37.9, 7.5
Basic fibroblast growth factor M27968 −1.1, −1.43.6, 3.3
B-cell CLL/lymphoma 7A X89984 −1.3, −1∼−8.2, ∼−8.3
BCR/ABL M15025 ∼1.8, 1.4∼−7.9, ∼−6.6
BRCA2 U43746 ∼−2.1, ∼1.8∼5.3, ∼5.1
CACCC box-binding protein L04282 −1.5, −1.5−3.2, −3.9
CD38 antigen (p45) D84276 −1, ∼1.2∼9.1, ∼8.5
Cell cycle-related kinase AF035013 ∼−4.5, ∼2.8∼13.2, ∼10.4
Cell division cycle 2-like 1 (PITSLRE proteins) M37712 −1.4, −1.3−3.9, −3.1
Chromobox homolog 6 H10776 −2.6, 3∼−12.0, ∼−12.4
Chromosome 21 open reading frame 5 AJ237839 1.5, 1.43.6, 4.4
Collagen, type XV, alpha 1 L25286 1, 1.23.3, 3.2
Cyclin B M25753 ∼−1.6, 1.94.1, 3.9
Cyclin B1 M25753 1.5, 1.53.5, 3.9
Cyclin D2 D13639 −1.1, 1.74.1, 4.3
Dermatopontin AL049798 −1.4, 2.27.4, 6.4
Disintegrin-like and metalloprotease (reprolysin type) AB002364 1.1, 2.53.5, 4.6
DKFZP564A032 protein AL050267 ∼−2.2, ∼2.4∼7.6, ∼7.2
DKFZP564O0823 protein AL080121 ∼1.7, ∼−2.6∼−8.6, ∼−8.5
DNA sequence from clone 71L16 on chromosome Xp11 AL022165 ∼1.3, −2.7∼−4.0, ∼−3.6
E74-like factor 1 (ets domain transcription factor) M82882 −1.1, −1.43.2, 3.3
Early growth response 2 (Krox-20 [Drosophila] homolog) J04076 ∼1.2, ∼2.1∼12.8, ∼15.4
Elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) X52896 ∼−8.5, 1.9∼52.0, 6.7
Epidermal growth factor receptor X00588 −1.4, 1.27.7, 10.5
ERCC5 excision repair protein L20046 −1.2, −1.2−3.1, −13.8
Erythropoietin receptor M60459 1.3, −1.2∼−11.7, −3.4
Formyl peptide receptor-like 1 M84562 −1, −1.6−5.4, ∼−9.9
Gamma-interferon-inducible protein (IP-30) J03909 1.1, 1.34.1, 3.3
GTP-binding protein (RAB4) M28211 1.1, −1.1−6, −5.7
GTP-binding protein overexpressed in skeletal muscle U10550 −8.2, −5.84.1, 3.5
Guanine nucleotide exchange factor L13857 ∼1.3, ∼2.9∼6.0, ∼7.0
H3 histone family, member B N35832 ∼−1.1, ∼1.8∼6.7, ∼6.8
Hepatitis B virus-associated factor (XAP4) U67322 1.2, 1.110.6, 10
Heat shock protein 3, 27 kDa Y17782 −2.9, −1.5−3, −3.1
Histidyl-tRNA synthetase U18937 −1.6, −1.6−4.2, −3.2
Homo sapiens BAC clone CTB-60N22 from 7q21 AI825798 1.2, ∼2.5∼3.9, ∼6.2
Homo sapiens cDNA W27604 ∼−3.9, ∼2.1∼3.1, ∼3.5
Homo sapiens cDNA AA160708 1.1, −13.3, 3.1
Homo sapiens cDNA AA203476 1.1, 2.54.2, 3.6
Homo sapiens cDNA, 3′ end AI887421 −2.4, −1.8∼−10.1, ∼−7.6
Homo sapiens cDNA, 3′ end AA156240 −1.6, −2−7.4, ∼−21.6
Homo sapiens cDNA, 3′ end AI093511 −1.4, −2.1−3.3, −4.4
Homo sapiens cDNA, 3′ end AI246894 1.5, ∼1.8∼3.4, ∼4.5
Homo sapiens clone 24438 mRNA sequence AF070647 ∼−1.8, ∼−2.3∼−4.6, ∼−4.1
MAD-3 M69043 −2.1, −23.5, 3.4
MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) S57212 ∼1.2, ∼2.5−9.5, ∼7.9
Major histocompatibility complex, class I, F AL022723 1.1, −1.23.4, 3.2
Matrilin 2 U69263 −1.1, −1.5∼−5.7, ∼−7.0
Microtubule-associated tau protein X14474 ∼2.0, ∼2.8∼7.8, ∼5.8
MIP-1a D90144 1.3, 1.16.9, 6.5
MIP-3b AB000887 ∼−2.5, ∼1.5∼6.7, ∼8.2
Monokine induced by gamma interferon X72755 ∼−2.5, ∼1.5∼11.8, ∼12.6
Msh (Drosophila) homeo box homolog 1 (formerly homeo box 7) M97676 2, 1.86.1, 7.9
Myeloid differentiation primary response gene (88 kDa) U70451 1.1, 1.24, 3.4
Nuclear antigen Sp100 U36501 −1, 1.95.7, 6.6
P55pik D88532 −1.2, 2.16.2, 4.7
Pancreatic polypeptide receptor 1 U42387 ∼8.2, −1∼−5.8, ∼−7.3
Phosphodiesterase 1A, calmodulin-dependent U40370 3, 1.44.5, 5.2
Phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma) U90907 1.3, 1.23.3, 3
Phosphorylase kinase, beta L19314 1.1, ∼2.8∼7.5, ∼6.6
Plasminogen activator inhibitor-1 J03764 −1, ∼−4.914, 9.6
Protein kinase C, nu AB015982 −1.1, −1.7∼−6.5, −6.1
Protein kinase Chk2 AF086904 ∼−3.0, −1.1∼13.1, ∼11.2
Protein tyrosine phosphatase (PAC-1) L11329 −1.6, ∼−1.5∼34.4, ∼27.8
Protein-tyrosine kinase (HEK7) L36644 ∼1.0, ∼−1.4∼4.4, ∼3.9
Putative DNA/chromatin binding motif AJ132440 −1.8, −1.4−5.4, −15
RANTES M21121 2.3, 1.276.6, 74.6
Ras inhibitor InfHG511-HT5111.2, 1.1−3.8, −5.5
Receptor-interacting serine-threonine kinase 2 AF117829 −1.8, 1.43.4, 3.2
Regulator of G-protein signaling 6 AF073920 1.2, −1.25.5, 4.9
Retinitis pigmentosa 2 (X-linked recessive) AJ007590 −1, 1.54.2, 4.7
Retinoic acid receptor responder (tazarotene induced) 3 AF060228 1.4, 1.34.6, 4.4
Serine protease AF015287 −1.1, 1.33.3, 3.1
Serine/threonine kinase 15 AF011468 −1.2, −1.8∼−22.3, ∼−13.1
Sjogren syndrome antigen A1 (52 kDa, ribonucleoprotein autoantigen SS-A/Ro) M62800 2, 1.75.9, 5.5
Solute carrier family 1 (glial high-affinity glutamate transporter), member 3 D26443 1, 1.15.6, 5
Steroid receptor (TR2-11) M29960 −1.7, −2.1∼−6.2, −3.4
Tachykinin, precursor 1 U37529 ∼−1.8, ∼2.0∼4.9, ∼4.3
Three prime repair exonuclease 1 AJ243797 −1.5, ∼1.9∼25.4, −30.8
Tissue inhibitor of metalloproteinases-2 (TIMP-2) U44385 −1.5, −1.2−4.4, −4.5
TNF-related apoptosis inducing ligand TRAIL U37518 1.5, 1.220.8, 18.2
Toll-like receptor 3 U88879 ∼1.1, 14.5, 4.7
Transcobalamin I (vitamin B12-binding protein, R binder family) J05068 −1.3, ∼1.3−4.7, ∼7.2
Transcriptional unit N143 AJ002572 ∼−2.2, −2.8∼−4.2, −7.2
Tumor necrosis factor alpha-inducible protein A20 M59465 −1.3, −1.63.7, 3.1
Tyrosine kinase-type receptor (HER2) M12036 ∼−2.8, −1.1∼−11.6, ∼−10.9
XIAP-associated factor 1 X99699 ∼−4.2, ∼−2.1∼−10.1, ∼9.6
zinc finger protein homologous to Zip-36 in mouse M92843 −6.6, −33.7, 3.2
  • a Nuc ID, nucleotide sequence identification or sequence accession number.

  • b Two fold change values were determined in independent experiments. A ∼ symbol in front of a fold change value indicates that the transcript was scored as absent in either the baseline or experimental sample and that the fold change was then calculated using the background noise value as the intensity for that comparison. The complete data set with difference calls can be accessed at http://www.molbio.princeton.edu/labs/shenk/browneetal2001/.