Table 4.

Genes modulated by HCMV in the presence of cycloheximid

GeneNuc IDaFold changeb
Angelman syndrome gene, E6-AP ubiquitin protein ligase 3A (UBE3A) AF002224 ∼29.5, ∼8.1
Beta nerve growth factor X52599 −5.4, ∼−8.4
CIG49 AF026939 17.9, 38.9
Cryptochrome 1 (photolyase-like) D83702 −3.3, −5.7
Cyclin-dependent kinase inhibitor 1B (p27, Kip1) AI304854 −7.6, ∼−5.8
Folate receptor 3 U08471 −3.8, ∼−3.9
GRO3 oncogene M36821 −6.2, ∼−7.9
Homo sapiens14A6CK DNA sequence X72882 −33.7, ∼3.2
Histone deacetylase 7B AB018287 −5.5, −12.3
Human mRNA for proto-oncogene protein D14497 −4.3, ∼−8.4
Hypothetical protein FLB6421 AI133727 26.5, ∼31.9
Inhibitor of apoptosis protein 1 U45878 −3.1, −3.7
Interferon, beta V00535 ∼65.1, ∼8.1
Interferon-induced 17-kDa/15-kDa protein M13755 8.6, 13.4
Interferon-induced 56-kDa protein M24594 3.9, 4.7
ISG-54K gene (interferon-stimulated gene) exon 2 M14660 29.6, ∼47.1
KIAA0354 gene product AB002352 −6, −6.4
KIAA0477 protein AB007946 −6.8, ∼−4.3
Melanoma growth stimulatory activity (MGSA) X54489 −3, −4.3
Mitogen-activated protein kinase kinase kinase 8 Z14138 −5.1, ∼−4.6
Novel human gene mapping to chomosome 13, similar to rat RhoGAP AL049801 −3.7, −3.1
Protein kinase C-alpha AF035594 ∼−10.3, ∼−4.3
rel proto-oncogene X75042 −4.4, ∼−4.4
Transforming growth factor beta-2 M19154 ∼−8.3, ∼−3.5
Tyrosine kinase arg gene mRNA M35296 −5.4, ∼−4.1
  • a Nuc ID, nucleotide sequence identification or sequence accession number.

  • b Two fold change values were determined in independent experiments. A ∼ symbol in front of a fold change value indicates that the transcript was scored as absent in either the baseline or experimental sample and that the fold change was then calculated using the background noise value as the intensity for that comparison. The complete data set with difference calls can be accessed athttp://www.molbio.princeton.edu/labs/shenk/browneetal2001/.