Table 5.

HIV-1 neutralization assays including IgG b12, IgG 2F5, Fab Z13, and IgG 4E10

IsolateSubtypeConcn of MAb (μg/ml) required for 50 or 90% inhibition of maximum p24 levels
IgG b12IgG 2F5Fab Z13IgG 4E10
50%90%50%90%50%90%50%90%
MNB0.00150.0150.131>40>405>50
HxBc2B0.0250.50.755>40>400.1510
JR-FLB0.40.82139513025>25
89.6b Ba 0.8>100>100>25>25
94ZW109C>50>50>50>50190250>50>50
CM235E>50>5019251702507.525
  • a —, experiment was not done.

  • b The results for 89.6 are from a single experiment only.