Table 1.

Effect of treatment with LZhuTRAIL or agonistic anti-R2 antibodies on IUPM

Treatment and cell typePatientIUPM in:
Control cellsTreated cells
LZhuTRAIL, resting memory cellsa 10.410.02
22.290.02
30.080.01
42.290.08
50.410.01
60.410.01
70.410.01
LZhuTRAIL, PBLb 10.410.41
20.410.01
30.410.01
40.410.01
Anti-TRAIL-R2, resting memory cellsc 12.292.29
22.292.29
37.182.29
47.182.29
Anti-TRAIL-R2, PBLd 12.290.41
20.410.01
32.292.29
42.292.29
  • a P = 0.03 for the difference between control and treated cells.

  • b P = 0.02 for the difference between control and treated cells.

  • c P = 0.13 for the difference between control and treated cells.

  • d P = 0.49 for the difference between control and treated cells.