Table 2.

Distribution of HSV particles (capsids and virions) in wild-type- and KΔUL37-infected Vero cells observed by TEM

VirusaDistribution of HSV particles [no. of particles (%)]
ExtracellularCytoplasmNucleusNuclear peripheryb
KOS271 (6.9)85 (2.2)297 (7.5)67 (1.7)
KΔUL37155 (3.9)c 842 (21.4)1,402 (35.7)817 (22.1)
  • a The total number of particles counted for both wild-type and mutant was 3,936 ( n = 20 cells for each virus).

  • b Particles within 2 μm of the nuclear periphery.

  • c The particles of KΔUL37 observed outside the cell were most likely light particles.