Table 1.

Plasma viral loads after vaginal challenge with various doses of SHIV162P4

AnimalChallenge doseaLog viral load in plasma on day:Day of death
7111421286090321376
J440600<2.64.05.36.66.26.06.5Day 174b
N083600<2.64.85.96.35.74.13.0<2.6<2.6Day 434c
I806600<2.63.65.16.65.2<2.6<2.6<2.6<2.6
N462300<2.62.84.76.45.7Not done<2.6<2.6<2.6
N321300<2.66.27.16.96.45.57.2Day 117d
I624300<2.64.25.65.75.3<2.6<2.6<2.6<2.6
M290100<2.6<2.63.75.06.3<2.66.0<2.6<2.6
L4921002.85.46.86.64.73.03.04.85.0
H658100<2.64.66.37.66.4<2.63.56.46.4Day 439e
  • a Challenge dose in TCID50s.

  • b Found dead. Autopsy findings: thymic atrophy, amyloidosis, emaciated, pneumonia.

  • c Found dead. Autopsy normal, suspect anesthetic death.

  • d Euthanized because of severe weight loss. Autopsy findings: emaciated, pneumonia, colitis.

  • e Euthanized. Autopsy findings: thymic atrophy, amyloidosis.