TABLE 2

Susceptibility of HCV to neutralization by MAbsa

TABLE 2
  • a (1) Data are the mean values of at least three experiments calculated from the data shown in Fig. 4 by using the log inhibitor versus normalized response curve in Prism v7.0. The symbol > indicates that the amount of antibody required to inhibit entry is greater than the highest concentration tested. Red indicates significantly more resistance than the parental WT virus (P < 0.001). Dark green and light green indicate significantly more sensitivity to neutralization than the parental WT virus (P < 0.001 and P = 0.004 to 0.007, respectively). White indicates no significant difference from the parental WT virus (P > 0.05). (2) The IC50 (μg/ml) of each MAb for the WT virus and fold changes in IC50 relative to the WT virus are shown. (3) NC, not converged (no P value calculated). Red, fold increase in resistance; green and white, fold increase in sensitivity.