Table 2.

LANAp activity in various cell lines

Plasmid Mean fold induction ± SD in cell linea:
BCBL-1 BC-3 LnCAP HeLa
pDD41 (−1490) 28 ± 627 ± 4 100 ± 30 40 ± 10
pDD43 (rev)8 ± 1 1b 10 ± 10 1
pDD83 (−279)22 ± 3 7 ± 2 160 ± 20 50 ± 10
pDD53 (−30) 2 ± 1 1 1 1
Simian virus 40 promoter 4 ± 1 2 ± 1 120 ± 20
Vector 1 1 11
  • a Shown are fold inductions ± SDs compared to vector control for triplicate experiments normalized to a cotransfected secreted alkaline phosphatase vector for various cell lines.

  • b The numeral 1 indicates luciferase activity at or below that of the vector control.