Table 1.

Binding of rabbit sera to heterologous Envs

Animal no.ImmunogenSerum dilution giving 50% binding
gp160gp120
IIIBJRCSFSF2RFBa-L89.6BK132IIIBJRCSFRF89.6BK132
2219gp1207,9401,1205,4403,6404,9203,29087021,0202,8104,7802,7502,440
2220gp1208,2001,5701,9902,0202,8702,1501,76023,1605,5104,4501,9904,100
2221gp1205,5301,1001,2101,2802,2401,59069011,5902,2502,3301,2502,120
Avg ± SD 7,223 ± 1,4721,263 ± 2662,880 ± 2,2512,313 ± 1,207 3,343 ± 1,4012,343 ± 866  1,107 ± 57318,590 ± 6,156 3,523 ± 1,7433,853 ± 1,3301,997 ± 750  2,887 ± 1,063
2164gp14022,2003,1206,9105,55010,4203,7201,73031,5405,0007,4003,8005,530
2165gp14023,7003,52015,6907,22017,5406,6501,20041,25012,74012,42010,4607,820
2166gp1408,4004,6605,3405,2909,6903,6002,36015,1806,1607,4104,5506,360
Avg ± SD18,100 ± 8,4343,767 ± 7999,313 ± 5,5776,020 ± 1,04712,550 ± 4,3374,657 ± 1,7271,763 ± 58129,323 ± 13,1767,967 ± 4,1749,077 ± 2,8956,270 ± 3,6486,570 ± 1,159
2144Denatured gp1409,2602,2903,9504,9206,0503,1704,8309,5102,3404,1802,6207,720