Table 3.

Neutralizing antibody titer to SHIV-HXB2 in rhesus macaque seraa

Animal no.ImmunogenTiter at study wk
MT-2 cell assayPBMC assay, wk 26
1012202631333753150
17951gp140187134<204241474923<20<2045
18001348159408445636904714692,016250
18066296109<20313703613<202035
18102868510811,31568640854315388280
18024None<20<20<20<204,0327055109684,380
18062<20<20<20<20<2025797934,514
  • a Neutralizing antibody titers are given as the reciprocal serum dilution at which 50% of cells were protected from virus-induced killing. Immunizations were performed on weeks 8 and 24. SHIV-HXB2 challenge was on week 27.