Table 1.

SIV-derived peptides that bind to Mamu-A*01 with IC50 values below 500 nMa

Peptide no. or virusProtein and amino acidsPeptideSequenceIC50 (nM)Reference
1Env 235–242Env_CL8CAPPGYAL1.9
2Pol 143–152Pol_LV10LGPHYTPKIV3.0
3Pol 51–61Pol_EA11EAPQFPHGSSA3.7
4Env 235–243 Env_CL9 CAPPGYALL5.5
5Env 729–738Env_ST10SPPSYFQTHT8.2
6Pol 621–629 Pol_SV9621 STPPLVRLV8.7
7Pol 588–596Pol_QV9QVPKFHLPV9.1
8Env 622–630 Env_TL9 TVPWPNASL10
9Vpx 102–111Vpx_GL10GPPPPPPPGL23
10Pol 474–483Pol_IL10IYPGIKTKHL23
11Pol 621–628Pol_SL8STPPLVRL26
12Pol 147–155Pol_YI9YTPKIVGGI26
13Gag 372–379Gag_LF8LAPVPIPF29
14Rev 87–96Rev_DL10DPPTNTPEAL39
15Pol 359–368Pol_GM10GSPAIFQYTM48
16Gag 372–380Gag_LA9LAPVPIPFA50
17Vpx 39–48Vpx_HV10HLPRELIFQV50
18Env 763–771Env_SI9SWPWQIEYI67
19Pol 957–964Pol_MI8MTPAERLI77
20Pol 34–43Pol_QF10QMPRQTGGFF78
21Pol 359–367Pol_GT9GSPAIFQYT82
22Gag 181–189 Gag_CM9 CTPYDINQM86
23Vif 75–82Vif_LL8LTPERGWL90
24Gag 170–177Gag_VL8VVPGFQAL99
25Vif 100–107Vif_VI8VTPDYADI103
26Vif 144–152Vif_QA9QVPSLQYLA141
27Tat 28–35Tat_TL8TTPESANL148
28Vif 14–22Vif_RW9RIPERLERW170
29Env 133–140Env_AV8AAPTSAPV175
30Gag 254–262Gag_QI9QNPIPVGNI196
31Env 431–439Env_YI9YVPCHIRQI210
32Env 728–736Env_ST9SSPPSYFQT220
33Vpx 8–18Vpx_II11IPPGNSGEETI241
34Gag 340–349Gag_VT10VNPTLEEMLT267
35Env 504–512Env_IT9ITPIGLAPT286
36Gag 149–157Gag_LW9LSPRTLNAW355
37Pol 692–700Pol_SV9692 SGPKTNIIV366
SIVEnv 235–243 Env_CL9 CAPPGYALL 25
SIVPol 621–629 Pol_SV9 STPPLVRLV 22
SIVEnv 622–630 Env_TL9 TVPWPNETL 25
SIVGag 181–189 Gag_CM9 CTPYDINQM 2, 44
SHIVEnv 431–439 Env_YI9 YAPPISGQI 22
  • a Previously defined Mamu-A*01-restricted SIV/SHIV CTL epitopes are shown in boldface.