Table 1.

NL4-3 in SCID-hu Thy/Liv mice

CohortDay postinoculationMouse no.% Livea% DPbCD4/CD8cp24 (pg/106 cells)
2141563831.3373
1640701.7909
1771752.4303
43185200.21,474
191430.061,565
20570.01576
32472950.62,795
82640.72,217
92190.72,262
10410.42,351
421342311.32,256
5141437370.7 NDd
1530370.5ND
211221150.24,416
1355130.63,664
163960.41,148
6122983812.3429
3184842.542
263248240.51,565
334190.51,502
  • a Percentage of events acquired on the FACScan that fall within the live-cell gate.

  • b Percentage of live cells that express CD4 and CD8 (i.e., are double positive [DP]).

  • c Ratio of percentages of CD4+CD8 and CD4 CD8+ thymocytes.

  • d ND, not determined.