Table 1.

Neutralizing antibody titersa of hyperimmune sera

VirusTiter of serumb
Anti-Ad2Anti-Ad5Anti-dlAd5NCAT-H2Anti-dlAd5NCAT-H2L2
Ad2>5,1200c 640160–320
Ad50c 5,12040–802,560–5,120
dlAd5NCAT-H21,280–2,560160–3206402,560
dlAd5NCAT-H2L2405,120160–3205,120
dlAd5NCAT-F7NDd 5,12040–805,120
  • a Inverse of dilution giving 50% neutralization.

  • b Serum sources: anti-Ad2 and anti-Ad5, ATCC (National Institute for Allergy and Infectious Diseases); anti-dlAd5NCAT-H2 and anti-dlAd5NCAT-H2L2, rat (without adjuvant).

  • c No detectable neutralization.

  • d Nd, not determined.