Table 1.

Cell susceptibility to DEN-2 PL046 infection

Cell line and no. of days p.i.Virus titer (PFU/ml)Immunofluorescence assayaImmunoblotting
K562
 21.0 × 105 ++
 49.5 × 106 ++
 62.0 × 106 ++
U937
 21.0 × 104 +/−
 41.0 × 104 +/−
 6<50+/−
HL-60
 2<50
 4<50
 6<50
THP-1
 2<50
 4<50
 6<50
  • a +/−, approximately 5% of the cells were positively stained by DEN-specific MAbs against E, NS1, and NS3 proteins.