Table 3.

Fraction of apoptotic HeLa cells in cultures infected during S phase or G1 a

VirusCells labeled with annexin V (mean % ± SD)
SG1
dl3093.1 ± 1.05.1 ± 1.2
dl15202.4 ± 0.93.4 ± 1.0
dl33771.1 ± 4.090.2 ± 5.0
Mock2.3 ± 0.82.9 ± 0.9
  • a Cells were infected at the stage of the cell cycle indicated with 10 PFU of virus per cell. At 24 h postinfection, cells were labeled with FITC-conjugated annexin V, and at least 300 cells were evaluated to determine the percentage of apoptotic cells.