Table 1.

EBV replication genes and expression plasmids

Viral geneFunctionClonec-MycaE2TANLSb
BMRF1Polymerase accessory factorRTS14DH295
BALF5DNA polymeraseRTS13DH312DH294
BALF2Single-stranded DNA binding proteinRTS12DH316JF3
BBLF2/3Primase-associated factorRTS25DH318JF6
  • a Protein is expressed as a fusion with an epitope (aa 425 to 434) from c-Myc.

  • b Protein is expressed as a fusion with the nuclear localization signal and transcriptional activation domain (aa 424 to 487) from EBV EBNA2.