Table 2.

Peak titers of wt and viable chimeric mutant viruses in LLC-MK2 and C6/36 cellsa

VirusbPeak titer (104 PFU/ml) (day postinfection) in:
LLC-MK2 cellsC6/36 cells
DEN2 wt>10 (6)>1,000 (3)
D2/WN-SL(mutA)1 (5)>100 (4)
D2/WN-SL(mutD)10 (6–8)>10 (5)
D2/WN-SL(mutF)>10 (8)10−2 (7)
D2-SL(a)>1 (5)>100 (6)
D2-SL(b)1 (5)>10 (5)
  • a Data were taken from results shown in Fig. 6A and B.

  • b See Fig. 2 and 4 for genotypes of mutant viruses.