Table 3.

Summary of the effects of antibody and soluble forms of gp42 on the ability of wild-type virus and virus lacking gp42 to infect B cells and the epithelial line SVKCR2

MAb or proteinProtein(s) reacting with MAb or proteinInfection in presence of MAb or proteina of:
B cells by:Epithelial cells by:
Wild-type virusgp42 virusWild-type virusgp42 virus
NoneNone+++
E1D1gH-gL+ND
F-2-1gp42ND+ND
ALVA 42HLA- DRND+ND
gp42.FcHLA- DR and gH-gL+
ΔN58HLA- DR+ND
ΔN90HLA- DR+ND
ΔN122HLA- DR±+ND
  • a +, infection present; −, infection absent; ±, low-level infection; ND, not done; gp42, gp42 negative.