Table 1.

Quantitation of viral protein in the brain and spleen

VirusMean viral protein (μg of total viral protein/g of tissue) ± SDaNo. of mice
BrainSpleenc
KP120 ± 39b 8,320 ± 4,3903
KP4115 ± 7.77,700 ± 2,5704
E53K/L56P17 ± 9.06,980 ± 2,5305
  • a Measured by antigen capture ELISA in 10% homogenates of brain and spleen harvested 20 days after neonatal i.p. inoculation. Values were extrapolated from standard curves of purified virus.

  • b Statistically different from values for KP41 and E53K/L56P (P < 0.001).

  • c The values are not statistically different from each other (P > 0.05).