Table 7.

Immunohistochemical analysis of muscle for markers of inflammation and immune‚ÄČactivationa

MarkerNaiveAAVAdenovirus
CD41440
CD81255
B2201612
CD251844
MHC II11252
B7-2119
CD11c12.14.6
  • a C57BL/6 mice were uninfected (mock) or injected with AAVlacZ or AdlacZ into the tibialis anterior. Ten days later, muscle was harvested and evaluated for the presence of the markers listed, using techniques of immunohistochemistry. Expression of the markers was quantified from multiple samples using morphometric techniques as described in Materials and Methods. Each sample is normalized to the level found in naive animals.