Table 2.

Characteristics of neutralizing MAbs against picornaviruses with known three-dimensional structures

Antibody (reference)Antigen (epitope)Receptor obstructedBinding valenceNeutralization
17-1A (32)HRV14 (1A)YesBi-Strong
12-1A (34)HRV14 (1A)YesBi-Strong
1-1A (34)HRV14 (1A)YesMono-Weak
8F5 (13)HRV2 (B)NoBi-Weak
3B10HRV2 (B)NoMono-Weak
SD6 (14)FMDV-C (GH loop)YesMono-Strong