Table 1.

Anti-HIV activity of SDF-1α, SDF-1β, MAb 12G5, and other compounds against wild-type, SDF-1αr e s, and AMD3100r e s viruses in MT-4 cellsa

Anti-HIV agentIC50 (μg/ml) for:
Wild-type virusSDF-1αresvirusAMD3100res virus
SDF-1α0.130>2>2
SDF-1β0.200>2>2
MAb 12G58>20>20
AMD31000.0060.0650.689
AMD27630.32.5>25
DS0.20.2>5
AR1771.11.5>5
AZT0.00060.00080.0005
  • a Virus yield was monitored in the cell-free supernatant from MT-4 cells 4 to 5 days after infection by a viral p24 antigen enzyme-linked immunosorbent assay. Results represent mean values from three to eight separate experiments.