Table 1.

Severity of pathological changes in different brain regionsa

MacaqueBasal gangliaFrontal cortexThalamusParietal cortexMidbrainCerebellum
17834000000
18031311110
18242222221
18033332222
18292232322
17850323222
• a Sections with more than 30 perivascular macrophage-rich cuffs were given a score of 3, sections with 10 to 30 perivascular cuffs were given a score of 2, and those with less than 10 perivascular cuffs were given a score of 1. The scores for all sections were totaled and divided by 6 (six regions were graded for each brain) to give the mean score (of a maximum of 3) for severity of CNS lesions shown in Table 2.