Table 1.

Clinical background and pathology appearance of study subjects

Study subjectAge (yr)Risk groupaCD4/μlHIV-related pathologybOther pathology
1 yr before death3 mo before deathPVWMGMBGBSCere
NA17334MH10+++/−+/−+/−+/−Toxoplasma
NA02149IVDU30087++++++/−+/−
NA12848MH124+/−+++++++++Toxoplasma
NA23428IVDU9030+++++++++Lymphoma
  • a MH, male homosexual; IVDU, intravenous drug user.

  • b Scored as − (negative), +/− (sparse pathology) +, (slight pathology), or +++ (severe pathology in different brain compartments). PV, perivascular; WM, white matter; GM, grey matter; BG, basal ganglia; BS, brain stem; Cere, cerebellum.