Table 5.

Summary of results after uncloned SIVmne challenge

GroupaProtection against uncloned SIVmne challenge
No. protected/totalPb
B1/3c 0.2
E3/30.003
F1/40.3
Control0/3
Cumulative controlsd 1/10
  • a See Table 1 and Materials and Methods for details of the immunization regimen.

  • b Calculated by using cumulative controls.

  • c One of the two infected animals, macaque 91250, was virus positive only by virus isolation at week 2 after challenge and by nested PCR at week 6.

  • d Including 10 animals infected intravenously with uncloned SIVmne in three separate experiments (76).