Table 1.

HIV-1 proviral copy numbers in hu-PBL-SCID mice infected with HIV-1 IIIB or SF162 at 2 h or 2 weeks after reconstitutiona

TissueMean proviral copy no./106cells at time of infection:
2 h2 wk
IIIBSF162IIIBSF162
Spleen620 ± 105870 ± 240125 ± 50325 ± 75
Lymph nodes605 ± 135440 ± 80230 ± 75450 ± 70
  • a Results are expressed as mean proviral copy number/106 cells ± standard error calculated for 9 mice/group. The sensitivity of the assay was tested by amplifying 8E5 T-cell DNA, which was serially diluted into SCID mouse DNA, as described in Materials and Methods.