Table 1.

GCV sensitivity in HFF, HEL97 cells, and HEL45 cells

Cell typeED50(mean ± SEM)a of:
AD169GDGrK17
HFF5 ± 0.634 ± 1.9
HEL975 ± 0.9 (P > 0.5)19 ± 3 (P < 0.02)
HEL455 ± 1.3 (P > 0.5)35 ± 8.6 (P > 0.05)
  • a Data are averages from three separate experiments, except for the HEL45 data, which are averages from two experiments. P values were calculated from a two-sample t test (two-tailed) comparing the average ED50to that seen in HFF.