Table 1.

Characteristics of individuals studied

CharacteristicTotalWSPS
No. of subjects 27 20  7
No. of subjects on the following drug combinationa (mean duration of follow-up):
 AZT-3TC-IDV (34 mo) 10  8  2
 AZT-3TC-RIT (28 mo)  5  3  2
 AZT-3TC-SQV/RIT (22 mo) 12  9  3
Age (yr)
 Mean ± SD33.3 ± 7.032.6 ± 6.535.2 ± 7.0
 Range24.2–53.926.7–53.924.2–51.2
Baseline CD4 cell count/μl
 Mean500517433
 Range47–1,224197–1,22447–838
Baseline viral loadb,c
 Mean596441610
 Range<0.5–4,760<0.5–4,76014.8–2,730
Time until viral loadb was <400 (days)
 Median 45 20 63
 Range0–1820–18233–132
Duration of viral loadd at <50 (mo)
 Median 20 20 19
 Range6–349–346–25
No. of episodes of viral loadd at 50–400
 Mean <1  3
 Range0–12–5
  • a AZT, zidovudine; 3TC, lamivudine; RIT, ritonavir; SQV, saquinavir; and IDV, indinavir.

  • b Viral load (branched DNA, copies per milliliter).

  • c Values are in thousands.

  • d Viral load (RT-PCR, copies per milliliter).