Table 1.

CDR3 sequences of Fabs to Ebola Zaire virus

FabHCDR3 sequenceaLCDR3 sequencea
Library K; IgG1 κ
 KZ51EVVVVPTAPTHNFYYYMDVAHRGGWPLS
 KS56, KZ52EGPRATGYSMADVFDIQQYYSAPLT
 KS14NEMSYDILTGPGDYYLDSEESYSAVFT
 KS5KYYSRLDVQQYFATVWT
 KS518RGSITLHREGNWFDPQQRGNWPPIT
Library L; IgG1 κ
 LS4TLSFAEVLYMDVFDIMPGTHWPPT
 LZ51TLSFAEVLYMDVFDIQQANTFPFT
Library E10; IgG1 λ
 ELZ510GYCSSTSCPPLFDSATWADSLSGVV
  • a HCDR3 and LCDR3 indicate heavy-chain and light-chain complementarity-determining region, respectively.