Table 1.

HLA-DR, CCR5 Δ32 genotypes, and zygosity identity of twin pairs and URDs used in this study

PairTwin 1Twin 2Twins’ zygositybURD 1URD2
HLACCR5 Δ32aHLACCR5 Δ32HLACCR5HLACCR5
Twin
 1KW (12, −)WTPW (12, −)WTConcordant
 2JB (0301, 03)WTNB (0301, 03)WTConcordant
 3MV (07, 0301)WTAV (07, 0301)WTConcordant
 4PG (07, 15)WTCG (07, 15)WTConcordant
 5KW (09, 15)HTMW (09, 15)HTConcordant
 6KF (12, 15)WTNF (12, 15)WTConcordant
 7MG (01, 02)WTRG (01, 02)WTConcordant
 8DH (08, 0101/2/4)HTBH (04, 0101/2/4)HTDiscordant
 9GS (03, 3/6)WTDS (03, 11)WTDiscordant
 10PG (02, 04)WTNG (02, 03)WTDiscordant
URD
 1KA (01, 02)WTBD (02, 04)WT
 2TA (07, 14)WTRF (03, 11)WT
 3AC (0301, 01)WTCR (14, 15)HT
 4JR (07, 17)WTMA (01, 14)WT
 5SD (07, 6)WTMS (07, −)WT
 6RN (02, 12)WTAS (07, 12)WT
 7ST (04, 6)WTNS (01, 02)HT
 8SH (01, 02)HTNH (09, −)WT
 9JR (09, 01)WTFL (14, 17)HT
 10MN (06, −)WTJT (02, 7)WT
  • a WT, wild type for CCR5; HT, heterozygous for CCR5 Δ32.

  • b Zygosity testing was carried out by using microsatellite markers and multiplex PCR (see Materials and Methods).