Table 4.

Mean genetic distances between sequences obtained in cells from individual donors or the cell pool and the in vivo-infected PBMC or the GBV-C prototype

SampleMean genetic distance ± SEM fora:
InoculumIn vivo PBMC from GBV-C-infected inoculum donorGBV-C prototype
Donor 10.055 ± 0.0100.013 ± 0.017  (P < 0.001)0.116 ± 0.009  (P < 0.001)
Donor 20.058 ± 0.0100.020 ± 0.018  (P < 0.001)0.117 ± 0.007  (P < 0.001)
Donor 30.053 ± 0.0070.008 ± 0.005  (P < 0.001)0.112 ± 0.006  (P < 0.001)
Donor 40.051 ± 0.0080.008 ± 0.006  (P < 0.001)0.114 ± 0.004  (P < 0.001)
Cell pool0.049 ± 0.0070.006 ± 0.006  (P < 0.001)0.113 ± 0.003  (P < 0.001)
  • a The P values, obtained by using Student’s t test, refer to the comparison of the mean genetic distances between each sample and the inoculum with those between the same sample and the in vivo PBMC or the GBV-C prototype.