Table 2.

Neurovirulence analysis of YF/JE chimerasa

VirusDose (log10 PFU)% Mortality (no. dead/no. tested)
YF5.2iv4100 (7/7)
YF/JE-S60 (0/8)
50 (0/7)
40 (0/7)
YF/JE-N4100 (5/5)
3100 (5/5)
2100 (5/5)
160 (3/5)
00 (0/5)
  • a ICR mice (4 weeks old) received YF5.2iv, YF/JE-S, or YF/JE-N at the indicated doses by intracerebral inoculation.