Table 2.

Summary of results from challenge studies

Challenge routeNo. of uninfected macaques/total no. of macaques challenged (% protection) with:
E11S cloneUncloned SIVmne
ImmunizedControlPImmunizedControlP
Intravenousa 14/16 (88)1/15 (7)<0.0013/10 (30)0/10 (0)0.2
Intrarectal3/4 (75)0/3 (0)0.1435/6 (83)0/6 (0)0.015
  • a Results of previous intravenous challenge studies (31) are included here for comparison.