Table 1.

Viral load in the tissues of +/+ and perf −/− mice after LCMV clone 13 infection (day 8 postinfection)

GroupLCMV titer (log10 PFU/g of tissue or ml of serum)a
SpleenLiverLungLymph nodesPancreasKidneyBrainSerum
+/+6.2 ± 0.18.2 ± 0.18.3 ± 0.17.3 ± 0.27.1 ± 0.67.1 ± 0.76.3 ± 0.45.2 ± 0.2
−/−6.5 ± 0.37.9 ± 0.18.0 ± 0.17.6 ± 0.36.7 ± 0.16.5 ± 0.16.0 ± 0.34.7 ± 0.1
  • a Six- to eight-week-old +/+ and −/− mice were infected i.v. with 2 × 106 PFU of LCMV clone 13. Eight days after infection virus titers in serum and various tissues were measured by plaque assay. The data shown are the average of four mice per group.