Table 1.

Cell lines, viruses, and tissue sources

Cell lineaVirusbLymphomacInductiondSpontaneous reactione
MDCC-UD01RB1BΔ4.5lac OvaryInoculate200/104
MDCC-UD02RB1BΔ4.5lac SpleenInoculate5/104
MDCC-UD03RB1BΔ4.5lac LiverInoculate50/104
MDCC-UD13RB1BVisceralf Inoculate<1/106
MDCC-UD22RB1BUS6lacgpt KidneyInoculateNDg
MDCC-UD23RB1BUS6gptlac OvaryInoculate40/104
MDCC-UD24RB1BUS6lacgpt LiverInoculate400/104
MDCC-UD25RB1BUS6lacgpt TestesInoculateND
MDCC-UD27RB1BUS6lacgpt KidneyContactND
MDCC-UD28RB1BUS6lacgpt TestesContactND
MDCC-UD29RB1BUS6lacgpt Visceralf ContactND
  • a Cell lines are named according to agreed nomenclature: MDCC (Marek’s Disease cell culture), followed by two-letter designation of institution (UD [University of Delaware]) and unique number.

  • b Viruses used to induce tumors: RB1BΔ4.5lac (61), RB1B (originally described in reference 74), and RB1BUS6lacgpt (4).

  • c Lymphoma site used to establish cell line.

  • d Inoculate, tumor induced by inoculated virus; contact, tumor induced by horizontally transmitted virus.

  • e Approximate number of PFU induced on secondary CEF after cocultivation with given number of cells from each cell line. Each number represents an average, rounded to the nearest 5 PFU obtained in at least three independent trials.

  • f Site of lymphoma ambiguous; more than one tumor taken; information lost on final establishment of line.

  • g ND, not determined.