Table 3.

Binding of sialylglycopolymers to H1N1 influenza viruses

Virus strainAbbreviationApparent association constant (Kass, μM−1 Neu5Ac)aRelative affinityb
3′SL-PAA6′SLN-PAA
Avian
 Turkey/MN/1661/81tyMN/8160160
 Mallard/TN/11464/85maTN/8560160
 Duck/Alberta/35/76dkAlb/7670170
 Duck/Bavaria/1/77dkBav/7770170
 Duck/Australia/749/80dkAus/8045145
Avian-like swine
 Swine/Arnsberg/6554/79swArn/7925151.7
 Swine/Netherlands/3/80swNet/8045104.5
 Swine/Germany/2/81swGer/8135103.5
 Swine/Belgium/1/83swBel/8335103.5
 Swine/Netherlands/12/85swNet/853083.8
 Swine/Italy/671/87swIta/879150.6
 Swine/Germany/8533/91swGer/9115200.8
 Swine/Schles.-Holstein/1/92swHol/9215300.5
Classical swine
 Turkey/MO/1/81tyMO/818250.3
 Swine/Hokkaido/2/81swHok/814140.3
 Swine/Italy/437/76swIta/7610250.4
 Turkey/NC/1/88tyNC/886110.6
  • a The binding assay was performed as described in Table 1, footnote a.

  • b See Table 1, footnote b.