Table 1.

Soluble GAG competition in paramyxoviruses

VirusMean GAG ED50(μg/ml)a ± SEM
LMW heparinBVL heparinDe-N-sulfated heparinChondroitin sulfate
A228.11 ± 0.230.28 ± 0.1129.96 ± 0.4285 ± 6.8
cp-523.38 ± 0.170.55 ± 0.143.46 ± 0.5411.5 ± 1.94
Measles virusb >250>250>250>250
  • a Results represent the mean ± the standard error of the mean for at least four separate experiments (P < 0.05).

  • b Inhibition of measles virus infectivity did not exceed 50% for any of the GAGs tested, and therefore no ED50 could be calculated.