Table 1.

Differences in the ability of influenza virus strains to infect murine Mφ

Virusa% of infected cellsb
Peritoneal MφAlveolar MφJ774 Mφ cell line
BJx10959 ± 1171 ± 653 ± 7
HKx3135 ± 742 ± 937 ± 12
PR83 ± 18 ± 13 ± 1
  • a Mφ monolayers in chamber slides were infected for 1 h with 106 PFU of influenza virus. At 8 to 10 h postinfection, cells were stained by immunofluorescence for expression of influenza virus NP.

  • b Data represent the mean percent infection ± 1 standard error of the mean from three experiments. MDCK cells infected under the same conditions showed >95% infection by all three viruses.