Table 2.

Correlations between CD8+ T-cell reactivities to HIV-1 proteins and various T-cell and viral parameters in group A patients on combination antiretroviral therapy

Test combinationDuration (wk)AntigenParameter
Test 1Test 2na rb P
CTLpIFN-γ0–128Gag450.48<0.01
Pol450.45<0.01
Env450.61<0.01
HIV-1 RNA0–12Gag25−0.41<0.05
Pol25−0.47<0.05
Env25−0.52<0.05
IFN-γCD4+ T cells0–12Gag17−0.18NSc
Pol170.68<0.05
Env17−0.27NS
CMV120.87<0.01
CD8+ T cells0–12Gag17−0.13NS
Pol170.61<0.05
Env170.36NS
CMV120.38NS
  • a n, number of determinations.

  • b Pearson correlation coefficient.

  • c NS, not significant (P > 0.05).