Table 4.

General properties of partially characterizeda and novel HERV families

FamilyCosmidPrimerSize (kb)Copy no.bGenomic organization
Partially characterized
 HERV.ADP AC005741 tRNAThr(?)8.460LTR-gag-pol-env-LTR
 HERV.FRD AC004022 tRNAHis 10.815LTR-ORF?-gag-pol-env-LTR
 HERV.XA AC000378 tRNAPhe 6.215LTR-gag-Δpol-Δenv-LTR
 HERV.HML5 AC004536 tRNAIle 7.845LTR-Δgag-DUT-pol-env-LTR
Novel
 HERV.Z69907 Z69907 No 5′ LTR∼6.630 gag-pol-Δ-env-LTR
 HERV.R (type b) AC004045(b)tRNAArg 8.715LTR-gag-pol-env-LTR
 HERV.F Z94277 tRNAPhe 8.715LTR-gag-pol-env-LTR
 HERV.F (type b) AC002416 tRNAPhe 6.830LTR-gag-Δpol-Δenv-LTR
 HERV.S AC004385 tRNASer 6.770LTR-gag-pol-env-LTR
 HERV.H49C23H49C23No LTRs∼6.070Δgag-pol-Δenv
  • a Properties of closely related HERV-containing cosmid clones.

  • b Number of elements containing domains 1 to 5 of RT, estimated by BLAST search followed by phylogenetic reconstruction.