Table 1.

Fusion host range of the HERV-W envelope glycoprotein

SpeciesTarget cell lineEnvelope glycoprotein expresseda
HERV-WA-Rless
QuailQT6
RatXC++
MouseNIH 3T3++
HamsterCear13++
CatCCC++
PigPAE++
MonkeyCOS-7+++
HumanA204++
B-1++
293+++
HeLa+++
A431++
TE671+++
  • a Fusogenic envelope glycoprotein was transiently expressed in cell-cell fusion assays. After 36 h of coculture with the indicated target cells, the fusion indices were determined: −, less than 1% fusion (background levels); +, 1 to 10% fusion; and ++, >10% fusion.