Table 1.

Plating efficiency of the UL34-negative recombinant vRR1072 on complementing and noncomplementing cells

VirusTiteraRelative efficiency:
143/1099EVeroHEL299VerobHEL299c
Δ305(1.6 ± 0.4) × 108 (9.9 ± 1.1) × 108 (2.6 ± 0.3) × 108 6.21.6
vRR1072(3.7 ± 0.3) × 107 (1.8 ± 0.9) × 106 (3.9 ± 0.5) × 107 0.051.1
vRR1072Rep(1.4 ± 0.7) × 107 (5.9 ± 1.4) × 107 (2.8 ± 0.2) × 107 4.11.9
  • a Each value is the mean and standard deviation from three independent titrations of the same viral stock. Any grouping of two or more infected cells was counted as a plaque.

  • b Calculated as titer on Vero cells divided by titer on complementing 143/1099E cells.

  • c Calculated as titer on HEL299 cells divided by titer on complementing 143/1099E cells.