TABLE 1

Env amino acid differences of the three wild-type SIVsmE660 strainsa

TierAmino acid
C1 at position:V1 at position:V2 at position:V4 at position:
4570134139140184185420425429432
1TSTAARIKKTR
2ANIASRIKRMQ
3ANTAKMNKTQ
  • a All of the amino acid differences among the three strains are shown. The locations of these differences are labeled by residue number as well as the domain in which they are found. C1 corresponds to constant region 1, and variable loops 1, 2, and 4 are labeled V1, V2, and V4, respectively. Residues that differ from the parental E660-FL14 tier 1 clone are in boldface type, and deletions are shown as a dash.