TABLE 3

Neutralizing antibody IC50 titers against the wild-type and mutant clones with monoclonal antibodies targeting the V2, V3, and CD4bs regions

TierCloneIC50 (μg/ml)
V2V3CD4bs
1wt0.0450.0160.028
ΔCT>50>50>50
2wt5.2600.0650.160
ΔCT>50>50>50
3wt>50>50>50
ΔCT>50>50>50