TABLE 2

Results of oral challenge with 5 g brain homogenatea

Recipient genotypeMean age at inoculation (days) ± SDNo. of intercurrent deaths before 6-mo cull (day postinoculation)No. of TSE-positive animals at 6-mo cullbNo. of intercurrent deaths at 6-mo cull (day postinoculation)No. of TSE-positive animals at 12-mo cullbNo. of intercurrent deaths at 12-mo cull (day[s] postinoculation)No. of TSE-positive animals at 24-mo cullbNo. of intercurrent deaths at 24-mo cull (day[s] postinoculation)No. of live animals (day postinoculation)
NN161 ± 971c1 (358)4d6 (487, 650, 667, 698, 723, 729)53 (750, 779, 788)
ND163 ± 781 (88)001 (681)07 (764, 1765, 1844, 1848, 2126, 2131, 2179)1 (>2,600)
NS125 ± 6801 (219)01 (721)05 (829, 1418, 1669, 1984, 2275)3 (>2,600)
DD138 ± 59002 (491, 719)05 (1143, 1466, 1723, 2147, 2175)3 (>2,450)
SS142 ± 461e (40)01 (247)02 (667, 645)05 (1213, 1291, 1401,1421, 1585, 2358)2 (>2,450)
  • a TSE-positive animals are indicated in boldface type, and animals with clinical signs of TSE are indicated in italic type.

  • b At each cull point, 5 animals per genotype were euthanized.

  • c Positive in the LRS only.

  • d Three animals were positive only in the LRS, and one was positive in the CNS and LRS.

  • e Not sampled.