TABLE 6

AcMNPV genes with strong signatures of positive selection within and between genomesa

GeneCategoryPosition in AcMNPV (kb)Mean dN/dSMK DoSbTajima's DPositive selection across lineagesPositive selection in AcMNPV
PolyhedrinEnvelope4.50.0770.611−5.463NoYes
Env-ProtEnvelope18.50.2380.575−4.644NoYes
LEF-8Transcription40.50.2690.430−3.787NoYes
LEF-3DNA binding57.70.3082.793−8.171NoYes
IAP-2Apoptosis610.4041.455−4.684NoYes
LEF-4Transcription76.51.2640.762−1.528YesYes
helicaseReplication80.62.0920.223−4.802YesYes
chitinaseHost infection105.20.9250.605−1.907YesYes
V-CATHHost infection106.90.2510.671−3.59NoYes
p24Capsid109.90.2291.182−6.01NoYes
e18Envelope125.10.1613−3.52NoYes
ec27Envelope125.30.1270.083−3.615NoYes
  • a Positions and gene names are given based on the AcMNPV genome, with mean dN/dS values giving the means of the best-fitting beta site and site model values for the given genes' orthology groups.

  • b DoS, direction of selection.