Table 3.

Detection of positive and negative strands of HCV RNA in serum and liver tissue samples from four patients with AIDS

PatientHCV RNA titera in:
Serum (genomic eq/ml)Liver tissue (genomic eq of RNA/μg)
Postive strandNegative strandPositive strandNegative strand
15 × 105 Negb 107 106
25 × 103 Neg105 104
35 × 104 Neg104 102
45 × 103 Neg103 102
  • a The presence and titers of the positive strand were determined by the MMLV RT-based assay, while the presence and titers of the negative strand were determined by the Tth-based assay.

  • b Neg, negative.