Table 6.

CTL precursor frequencies of infected vaccineesa

VolunteerStudy dayImmunogenFrequency per 106 PBMC of CTL precursors vsb:
NYCBHGagRTIIIbMNRFSF2Nef
C06537MN1 296 NDND2235NDND
664MN246 1,528 ND231322
664MN3433 1,288 347 485842 250
664MN50 133 1,499 106 212826 136
C09642SF-21268115811204
C10679MN15 415 ND2022 729 NDND
909MN16727 94 32211
C11834MN35 278 ND3763630ND
C13656SF-215 86 ND402640NDND
763SF-270 196 ND36433113ND
C18832Placebo1435 62 227
C20730SF-2316 57 1339461314
730SF-2213142318173010
C21917SF25 147 419295 134
917SF21 159 17263133 148
C241172MN291346362920333
  • a Determined by the method of Koup et al. (84).

  • b For a background value against the NYCBH control of <50/106 PBMC, a precursor frequency of 50/106 PBMC above background is considered significant (corresponding to 1/20,000 cells). For a background between 50 and 100/106 PBMC (e.g., subject C13), a precursor frequency of >150/106 is considered significant. Significant values are in boldface.